I think that whatever the case may be, that teaching the students some part of the course in a science class would take some time to implement. That is, time away from the science content. Some quick thoughts would be:
They could make web pages about what they are studying and have some kind of research component.
They could do lab write ups as web pages.
They could have a website that would act like a digital journal to keep track of experiments and their results.
Unit 3 - I think that the game lab would be more difficult to implement for the reason stated above.
Physics: Some kind of simulation using basic linear motion equations. The basic projectile motion comes to mind.
They could make animations that were mini lessons on a topic. Like a tutorial video.
This is a really interesting idea and it would be amazing to see some people come up with a more detailed plan to implement in the classroom. Maybe some starter projects to get students going. Hopefully some other will chime in and we can crowdsource this.